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Citaat:
An ecklonia cava enzymatic extract (35% Dieckol) appears to promote hair growth when the solution is applied to rats (0.5% of solution) and in vitro where 0.05% Dieckol promoted proliferation of Dermal Papillae cells by 113.5% of control.[60] This hair promoting effect was abolished when incubated with tolbutamide (an inhibitor of potassium channels), which establishes that Ecklonia Cava has similar mechanisms to Minoxidil.[60]
100ug/mL was able to inhibit 5α-reductase activity by 66.1%, which was not significantly different than Finasteride (despite the latter, at 2nM, inhibiting 94.6% activity) yet isolated Dieckol was found to have similar activity to Finasteride (both inhibiting 95.1% of 5α-reductase activity when Finasteride was at 2nM and Dieckol at 100ug/mL).[60]
Appears to have dual inhibitory potential on 5-alpha reductase enzymes and can also promote hair regrowth with a mechanism similar to Minoxidil (although comparative potency is unknown)
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