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Oud 23 november 2020, 20:13   #128
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Geregistreerd: 12 augustus 2016
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Geslacht:
Finasteride-induced secondary infertility associated with sperm DNA damage

Conclusion(s)

The significant reduction in DFI within 3 months of finasteride cessation and continued improvement suggests a causal link between finasteride and sperm DNA damage. We hypothesize that low-dose finasteride may exert a negative influence on sperm DNA integrity, resulting in increased pregnancy losses. We suggest that in infertile men using finasteride, sperm DFI should be measured in addition to semen parameters, and a trial of discontinuation of finasteride may be warranted.


https://www.sciencedirect.com/scienc...15028211000161
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