[Pionier]

Trouwens sterk aangeraden om te stoppen met fina als je aan kinderen wilt beginnen. (en best voor je persoonlijke gezondheid om voor altijd te stoppen natuurlijk)


There are warnings from many medical sources NOT to use Finasteride and have unprotected sex should your partner be pregnant.

1. This information was released by Merck via the FDA in 2011. https://www.google.com/url?sa=t&sour...ognrVif0OszxLF

https://www.accessdata.fda.gov/drugs...MG_MEDR_P1.PDF
"Abnormal male genital development is an expected consequence when conversion of testosterone to 5?dihydrotestosterone (DHT) is inhibited by 5?-reductase inhibitors. These outcomes are similar to those reported in male infants with genetic 5?-reductase deficiency. Women could be exposed to finasteride through contact with crushed or broken PROPECIA tablets or semen from a male partner taking PROPECIA…"


2. The Drugs.com article on Finasteride states: https://www.drugs.com/pregnancy/finasteride.html
"US FDA pregnancy category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits…Finasteride is present in semen and therefore may pose a risk to the fetus. Male patients should be instructed to wear a condom during intercourse with women of childbearing potential or discontinue finasteride. The drug should be discontinued in patients wishing to conceive a child."


3. The electronic medicines compendium https://www.medicines.org.uk/emc/pro...044/smpcstates: "Small amounts of finasteride have been recovered from the semen in subjects receiving finasteride 5 mg/day. It is not known whether a male fetus may be adversely affected if his mother is exposed to the semen of a patient being treated with finasteride. When the patient’s sexual partner is or may potentially be pregnant, the patient is recommended to minimise exposure of his partner to semen."


4. An extremely high percentage of post-marketing reports of exposure to Finasteride during pregnancy via Semen resulted in genital birth defects. https://www.medicines.org.uk/emc/product/2194/smpc"
"During continual collection of adverse experiences, post-marketing reports of exposure to finasteride during pregnancy via semen of men taking 1 mg or higher doses have been received for eight live male births, and one retrospectively -reported case concerned an infant with simple hypospadias. Causality cannot be assessed on the basis of this single retrospective report and hypospadias is a relatively common congenital anomaly with an incidence ranging from 0.8 to 8 per 1000 live male births. In addition, a further nine live male births occurred during clinical trials following exposure to finasteride via semen, during pregnancy, and no congenital anomalies have been reported."
NOTE: That's 1 out of 17 reports of paternal exposure resulting in a congenital defect which is extremely high.


5. Handbook of Systemic Drug Treatment in Dermatology edited by Sarah H. Wakelin, Howard I. Maibach, Clive B. Archer. "It is not known whether a male fetus may be adversely affected by in utero exposure to the semen of a man treated with finasteride or duasteride, but condom use is advised."


6. Back in 1997 it was requested Merck test and release the No Observable Effect Level dose for oral administration of finasteride. This was never done or they never released the findings: https://www.accessdata.fda.gov/drugs...1MG_PHARMR.PDF
Thus there is NO proven safe amount of finasteride to be received orally at all by pregnant women that has been proven NOT to cause birth defects, including in semen during oral sex.


7. 'Drug related safety issues affecting pregnancy outcome and concerning risk minimisation measures' by Crijns, Hubertina Johanna Maria Josephina. This states "Presence of drugs in seminal fluid could interfere with embryonic or foetal development because of a direct effect on the uterus or the vaginal mucosa during sexual intercourse during pregnancy." Finasteride directly lowers DHT or Dihydrotestosterone, which is the most critical hormone for male genital development during pregnancy in fetuses.





My Story: Taking Finasteride during my partner's pregnancy resulted in my son having genital birth defects



https://www.reddit.com/r/finasteride...tm_term=hjn7zh