November 11, 2020
Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride
Findings This pharmacovigilance case-noncase study of 3282 users of finasteride used VigiBase, the World Health Organization’s global database of individual case safety reports, and found a disproportional signal of suicidality, depression, and anxiety associated with finasteride use for alopecia in patients younger than 45 years. No such signal was associated with drugs that had different mechanisms of action but similar indications or with drugs that had similar mechanisms and adverse effect profiles.
https://jamanetwork.com/journals/jam...stract/2772818