NEW.. Androgenetic alopecia in men aged 40-69 years: prevalence and risk factors.

[pindakaas]

Androgenetic alopecia in men aged 40-69 years: prevalence and risk factors.

Severi G, Sinclair R, Hopper JL, English DR, McCredie MR, Boyle P, Giles GG.

Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, ItalyDepartment of Dermatology, St Vincent's Hospital, Melbourne, Australia Centre for Genetic Epidemiology, University of Melbourne, Melbourne, VIC, Australia Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton South, VIC 3053, Australia Department of Preventive Medicine, University of Otago, New Zealand and Cancer Epidemiology Research Unit, New South Wales Cancer Council, Sydney, Australia.

BACKGROUND: The epidemiology of androgenetic alopecia (AGA) is not fully understood. Although a strong genetic basis has long been identified, little is known of its non-genetic causes. OBJECTIVES: To estimate the prevalence of and to determine risk factors for AGA in men aged 40-69 years in Australia. METHODS: Men (n = 1390) were recruited at random from the electoral rolls to serve as controls in a population-based case-control study of prostate cancer. All were interviewed in person and direct observations of AGA were made. Men were grouped into the following categories; no AGA, frontal AGA, vertex AGA and full AGA (frontal and vertex AGA). Epidemiological data collected from these men were used for an analysis of risk factors for each AGA category using unconditional logistic regression with AGA category as the response variable adjusting for age, education and country of birth. RESULTS: The prevalence of vertex and full AGA increased with age from 31% (age 40-55 years) to 53% (age 65-69 years). Conversely, the proportion of men with only frontal AGA was very similar across all age groups (31-33%). No associations were found between pubertal growth spurt or acne, reports of adult body size at time of interview, urinary symptom score, marital status, or current smoking status or duration of smoking and the risk of any form of AGA. The consumption of alcohol was associated with a significant increase in risk of frontal and vertex AGA but not full AGA. Men with vertex AGA had fewer female sexual partners but average ejaculatory frequency did not differ between men in different AGA categories. Reported weight and lean body mass at reaching maturity at about 21 years of age were negatively associated with vertex balding (P for trend < 0.05) but not with frontal AGA or full AGA. CONCLUSIONS: Evidence for environmental influences on AGA remains very slight. Our study failed to confirm previously reported or hypothesized associations with smoking and benign prostatic hypertrophy. The associations that we found with alcohol consumption and with lean body mass at age 21 years would be worthy of further research if they were able to be replicated in other studies.

http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract

[Jack]

erg goed onderzoek, ben wel bang dat ik eigenlijk wat mider moet gaan drinken wat dat is dus duidelijk niet echt goed voor je haar